Scientific Studies Clinical Trials Scientific Research Peer Reviewed Articles Product InformationPhosphatidyiSerine (PS) and Alpha-Glycerylphosphorylcholine (AGPC) PhosphatidyiSerine (PS) Although PhosphatidyiSerine (PS) is derived from soy it does not contain any soy proteins which are the critical factor when determining if an ingredient causes allergic reactions to those who may be sensitive to soy. It is unlikely that PhosphatidyiSerine (PS) will cause an allergic reaction to those with or without soy allergies. Technical Data Sheet 010910 FDA’s Food Allergen Labeling and Consumer Protection Act of 2004 (21 usc 343) Section 203: Food Labeling; Requirement Of Information Regarding Allergenic Substances For:
Labeling Statement Under the section entitled, (c) Conforming Amendments, within FDA’s Food Allergen Labeling and Consumer Protection Act of 2004 (21 USC 343), all of the above listed specialty ingredient products are exempted as “major food allergens” from allergenic labeling, since they are ingredients derived from highly refined (soybean) oil. Additional Allergenicity Information 1) This is to certify that all of the above listed specialty ingredient products do not contain soy, peanuts, tree nuts, eggs, milk, fish, crustacean (shellfish), wheat, corn, yeast, or gluten. 2) This is to certify, that additionally, all of the above listed specialty ingredient products are non-allergenic, and that they are produced by Chemi S.p.A., Milan, Italy, and I or ITF Chemical Ltda., Camacari, Brazil, in contained environments within dedicated manufacturing facilities, that have no exposure to other potential allergenic food compounds, including, but not limited to soy, peanuts, tree nuts, eggs, milk, fish, crustacean (shellfish), wheat, corn, yeast, or gluten.
Accepted 31 October 2002.
Background: Parallel with the development of hypotheses regarding cholinergic involvement in geriatric memory dysfunction, the first attempts to treat patients with Alzheimer’s disease (AD) involved the cholinergic-precursor loading approach. Despite encouraging early results, well-controlled clinical trials did not confirm a clinical utility of cholinergic precursors such as choline and lecithin (phosphatidylcholine) in AD. Objective: This study assessed the efficacy and tolerability of the cholinergic precursor choline alfoscerate (CA) in the treatment of cognitive impairment due to mild to moderate AD. Methods: In this multicenter, double-blind, randomized, placebo-controlled trial, patients affected by mild to moderate dementia of the Alzheimer type were treated with CA (400-mg capsules) or placebo capsules, 3 times daily, for 180 days. Efficacy outcome measures that were assessed at the beginning of the investigation and after 90 and 180 days of treatment included scores of the Alzheimer’s Disease Assessment Scale-Cognitive Subscale (ADAS-Cog), the Mini-Mental State Examination™ (MMSE), the Global Deterioration Scale (GDS), the Alzheimer’s Disease Assessment Scale-Behavioral Subscale (ADAS-Behav), all items of the Alzheimer’s Disease Assessment Scale (ADAS-Total), and the Clinical Global Impression (CGI) scale. The Global Improvement Scale (GIS) score was assessed after 90 and 180 days of treatment. http://www.clinicaltherapeutics.com/article/S0149-2918(03)90023-3/pdf 1. PS, Cortisol, GH And Test. Response to Exercise 2. Muratorio-A-GPC v. CDP-Choline-040610 3. Cholinergic Precursors And Cog. Impairment 4. A-GPC-Power Output Study-Ziegenfuss-ISSN-060908 5. A-GPC & GH Response-ceda-011309 6. 18 Thomas Crook PS Article 7. 9 Influence of PS on mood and Heart Rate 8. 7 Comparative Study following AGPC 9. 6 Cognitive Improvement with AGPC 10. 4 Cortisol, Stress, and Health Huperzine A is a naturally occurring asfound in the plant firmossHuperzia serrata
Many studies on Huperzine have been completed including this multi-center, double blind, placebo controlled trial to determine whether natural Huperzine-A improves cognitive function of patients with Alzheimer’s disease.
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